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PKNCA: Perform Pharmacokinetic Non-Compartmental Analysis
Compute standard Non-Compartmental Analysis (NCA) parameters for typical pharmacokinetic analyses and summarize them.
Getting started
README.md
AUC Calculation with PKNCA"
AUC integration methods"
Computing NCA Parameters for Theophylline"
Data Imputation"
Half-Life Calculation"
Half-life calculation with Tobit regression"
Introduction to PKNCA and Usage Instructions"
Methods Used for Dose-Aware Concentration Interpolation/Extrapolation"
Noncompartmental evaluation of time to steady-state"
Options for Controlling PKNCA"
PKNCA Training Sessions"
PKNCA Validation"
Post-Processing"
Selection of Calculation Intervals"
Sparse NCA Calculations"
Superposition of Pharmacokinetic Data"
Unit Assignment and Conversion with PKNCA"
Writing PKNCA Parameter Functions"
Browse package contents
Package details |
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| Author | Bill Denney [aut, cre] (ORCID: <https://orcid.org/0000-0002-5759-428X>), Clare Buckeridge [aut], Gerardo Jose Rodriguez [aut] (ORCID: <https://orcid.org/0000-0003-1413-0060>), Sridhar Duvvuri [ctb] |
| Maintainer | Bill Denney <wdenney@humanpredictions.com> |
| License | AGPL-3 |
| Version | 0.12.1 |
| URL | https://humanpred.github.io/pknca/ https://github.com/humanpred/pknca http://humanpred.github.io/pknca/ |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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