auc_integrate: Support function for AUC integration
In PKNCA: Perform Pharmacokinetic Non-Compartmental Analysis

auc_integrate

R Documentation

Support function for AUC integration

Support function for AUC integration

auc_integrate(
  conc,
  time,
  clast,
  tlast,
  lambda.z,
  interval_method,
  fun_linear,
  fun_log,
  fun_inf
)

`conc`	Measured concentrations
`time`	Time of the measurement of the concentrations
`clast`	The last concentration above the limit of quantification
`tlast`	Time of last concentration above the limit of quantification (will be calculated, if not provided)
`lambda.z`	The elimination rate (in units of inverse time) for extrapolation
`interval_method`	The method for integrating each interval of `conc`
`fun_linear`	The function to use for integration of the linear part of the curve (not required for AUC or AUMC functions)
`fun_log`	The function to use for integration of the logarithmic part of the curve (if log integration is used; not required for AUC or AUMC functions)
`fun_inf`	The function to use for extrapolation from the final measurement to infinite time (not required for AUC or AUMC functions.