OneComp_Coefficient_Exponent: Convert pharmacokinetic parameters for one compartment model

In PKconverter: The Parameter Converter of the Pharmacokinetic Models

Description

Calculate pharmacokinetic parameters with parameters (A and alpha) in one compartment model "Aexp(-alpha)"

Usage

OneComp_Coefficient_Exponent(A,alpha,A.sd=NA,alpha.sd=NA,
           covar=c(Aalpha=NA),...)

Arguments

A	parameter in one compartment model "Aexp(-alpha)"
alpha	parameter in one compartment model "Aexp(-alpha)"
A.sd	standard error of A
alpha.sd	standard error of alpha
covar	covariances among parameters
...	arguments to be passed to methods

References

http://www.nonmemcourse.com/convert.xls

Examples

OneComp_Coefficient_Exponent(A=0.125,alpha=0.5,A.sd=0.002,alpha.sd=0.009)

Example output

        Parameter Estimate    Std.err
Vdss         Vdss 8.000000 0.12800000
V1             V1 8.000000 0.12800000
Cl1           Cl1 4.000000 0.09633276
k10           k10 0.500000 0.00900000
alpha       alpha 0.500000 0.00900000
t_alpha   t_alpha 1.386294 0.02495330
True_A     True_A 0.125000 0.00200000
Frac_A     Frac_A 1.000000 0.00000000

PKconverter documentation built on Feb. 6, 2020, 5:08 p.m.