OneComp_Volume_Clearance: Convert pharmacokinetic parameters for one compartment model

In PKconverter: The Parameter Converter of the Pharmacokinetic Models

Description

Calculate pharmacokinetic parameters with volume of distribution (V1) and clearance (Cl1)

Usage

OneComp_Volume_Clearance(V1,Cl1,V1.sd=NA,Cl1.sd=NA,
        covar=c(V1Cl1=NA),...)

Arguments

V1	The volume of distribution of compartment 1
Cl1	Clearance from compartment 1
V1.sd	standard error of V1
Cl1.sd	standard error of Cl1
covar	covariances among parameters
...	arguments to be passed to methods

References

http://www.nonmemcourse.com/convert.xls

Gabrielsson and Weiner(2006) Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Swedish Academy of Pharmaceutical Sciences.

Examples

OneComp_Volume_Clearance(V1=8,Cl1=4,V1.sd=0.01,Cl1.sd=0.01)

PKconverter documentation built on Feb. 6, 2020, 5:08 p.m.