bin2lin: binomial to linear regression conversion
In coloc: Colocalisation Tests of Two Genetic Traits
bin2lin R Documentation
binomial to linear regression conversion
Description
Convert binomial to linear regression
Usage
bin2lin(D, doplot = FALSE)
Arguments
D
standard format coloc dataset
doplot
plot results if TRUE - useful for debugging
Details
Estimate beta and varbeta if a linear regression had been run on a
binary outcome, given log OR and their variance + MAF in controls
sets beta = cov(x,y)/var(x) varbeta = (var(y)/var(x) -
cov(x,y)^2/var(x)^2)/N
Value
D, with original beta and varbeta in beta.bin,
varbeta.bin, and beta and varbeta updated to linear estimates
Author(s)
Chris Wallace
coloc documentation built on Oct. 3, 2023, 5:07 p.m.
R Package Documentation
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| bin2lin | R Documentation |
binomial to linear regression conversion
Description
Convert binomial to linear regression
Usage
bin2lin(D, doplot = FALSE)
Arguments
D |
standard format coloc dataset |
doplot |
plot results if TRUE - useful for debugging |
Details
Estimate beta and varbeta if a linear regression had been run on a binary outcome, given log OR and their variance + MAF in controls
sets beta = cov(x,y)/var(x) varbeta = (var(y)/var(x) - cov(x,y)^2/var(x)^2)/N
Value
D, with original beta and varbeta in beta.bin, varbeta.bin, and beta and varbeta updated to linear estimates
Author(s)
Chris Wallace
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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