est_cond | R Documentation |
Internal helper function for est_all_cond
est_cond(x, LD, YY, sigsnps, xtx = NULL)
x |
coloc dataset |
LD |
named matrix of r |
YY |
sum((Y-Ybar)^2) |
sigsnps |
names of snps to jointly condition on |
xtx |
optional, matrix X'X where X is the genotype matrix. If not available, will be estimated from LD, MAF, beta and sample size (the last three should be part of the coloc dataset) |
data.table giving snp, beta and varbeta on remaining snps after conditioning
Chris Wallace
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