sdY.est: Estimate trait variance, internal function
In coloc: Colocalisation Tests of Two Genetic Traits
sdY.est R Documentation
Estimate trait variance, internal function
Description
Estimate trait standard deviation given vectors of variance of coefficients, MAF and sample size
Usage
sdY.est(vbeta, maf, n)
Arguments
vbeta
vector of variance of coefficients
maf
vector of MAF (same length as vbeta)
n
sample size
Details
Estimate is based on var(beta-hat) = var(Y) / (n * var(X))
var(X) = 2maf(1-maf)
so we can estimate var(Y) by regressing n*var(X) against 1/var(beta)
Value
estimated standard deviation of Y
Author(s)
Chris Wallace
coloc documentation built on Oct. 3, 2023, 5:07 p.m.
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| sdY.est | R Documentation |
Estimate trait variance, internal function
Description
Estimate trait standard deviation given vectors of variance of coefficients, MAF and sample size
Usage
sdY.est(vbeta, maf, n)
Arguments
vbeta |
vector of variance of coefficients |
maf |
vector of MAF (same length as vbeta) |
n |
sample size |
Details
Estimate is based on var(beta-hat) = var(Y) / (n * var(X)) var(X) = 2maf(1-maf) so we can estimate var(Y) by regressing n*var(X) against 1/var(beta)
Value
estimated standard deviation of Y
Author(s)
Chris Wallace
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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