Olkin1995: Thrombolytic Therapy after Acute Myocardial Infarction

Description Format Source Examples

Description

Meta-analysis on Thrombolytic Therapy after Acute Myocardial Infarction

Format

A data frame with the following columns:

author first author
year year of publication
ev.exp number of events in experimental group
n.exp number of observations in experimental group
ev.cont number of events in control group
n.cont number of observations in control group

Source

Olkin I (1995): Statistical and theoretical considerations in meta-analysis. Journal of Clinical Epidemiology, 48, 133–46

Examples

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data(Olkin1995)
summary(metabin(ev.exp, n.exp, ev.cont, n.cont, data = Olkin1995))

Example output

Loading 'meta' package (version 4.15-1).
Type 'help(meta)' for a brief overview.
Number of studies combined: k = 70

                         RR           95%-CI     z  p-value
Fixed effect model   0.7728 [0.7342; 0.8135] -9.84 < 0.0001
Random effects model 0.7667 [0.7046; 0.8342] -6.17 < 0.0001

Quantifying heterogeneity:
 tau^2 = 0.0125; tau = 0.1118; I^2 = 17.2% [0.0%; 39.1%]; H = 1.10 [1.00; 1.28]

Test of heterogeneity:
     Q d.f. p-value
 83.33   69  0.1150

Details on meta-analytical method:
- Mantel-Haenszel method
- DerSimonian-Laird estimator for tau^2
- Mantel-Haenszel estimator used in calculation of Q and tau^2 (like RevMan 5)
- Continuity correction of 0.5 in studies with zero cell frequencies

meta documentation built on Sept. 14, 2021, 5:14 p.m.