amlodipine: Amlodipine for Work Capacity

In meta: General Package for Meta-Analysis

Amlodipine for Work Capacity

Description

Meta-analysis on the effect of amlodipine on work capacity.

This meta-analysis is used as a data example in Hartung and Knapp (2001).

Format

A data frame with the following columns:

study	study label
n.amlo	number of observations in amlodipine group
mean.amlo	estimated mean in amlodipine group
var.amlo	variance in amlodipine group
n.plac	number of observations in placebo group
mean.plac	estimated mean in placebo group
var.plac	variance in placebo group

Source

Hartung J & Knapp G (2001): On tests of the overall treatment effect in meta-analysis with normally distributed responses. Statistics in Medicine, 20, 1771–82

See Also

metacont

Examples

data(amlodipine)

m <- metacont(n.amlo, mean.amlo, sqrt(var.amlo),
  n.plac, mean.plac, sqrt(var.plac),
  data = amlodipine, studlab = study,
  method.tau = "DL")
m.hk <- update(m, method.random.ci = "HK")

# Same results for mean difference as in Table III in Hartung and
# Knapp (2001)
#
vars.common <- c("TE.common", "lower.common", "upper.common")
vars.random <- c("TE.random", "lower.random", "upper.random")
#
res.common <- as.data.frame(m[vars.common])
names(res.common) <- vars.random
#
res.md <- rbind(res.common,
  as.data.frame(m[vars.random]),
  as.data.frame(m.hk[vars.random]))
#
res.md <- round(res.md, 5)
#
row.names(res.md) <- c("CE", "RE", "RE (HaKn)")
names(res.md) <- c("Absolute difference", "CI lower", "CI upper")
#
res.md

meta documentation built on Oct. 31, 2024, 5:07 p.m.