Description Usage Arguments Details Value Author(s) References Examples
Remove mutation types that account for a total number of mutations below a defined threshold.
1 | removeWeak(input_mutCounts, params)
|
input_mutCounts |
numeric matrix of Mutation Counts |
params |
object (list) including all parameters required for running the analysis |
This is one of the core functions included in the original mutSignatures R library, and in the WTSI MATLAB framework. This is an internal function.
List including two elements:
More info and examples about the mutSignatures R library: https://www.data-pulse.com/dev_site/mutsignatures/
Oncogene paper, Mutational Signatures Operative in Bladder Cancer: https://www.nature.com/articles/s41388-017-0099-6
Damiano Fantini, damiano.fantini@gmail.com
More information and examples about mutational signature analysis can be found here:
GitHub Repo: https://github.com/dami82/mutSignatures/
More info and examples about the mutSignatures R library: https://www.data-pulse.com/dev_site/mutsignatures/
Sci Rep paper, introducing mutS: https://www.nature.com/articles/s41598-020-75062-0/
Oncogene paper, Mutational Signatures Operative in Bladder Cancer: https://www.nature.com/articles/s41388-017-0099-6
WTSI framework: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588146/
1 2 3 4 5 | x <- mutSignatures:::getTestRunArgs("removeWeak")
nrow(x$data)
y <- mutSignatures:::removeWeak(input_mutCounts = x$data, params = x$params)
nrow(y)
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