quantile.normalize: Perform quantile normalization of intensity data.

In andrewparkermorgan/argyle: Basic interface and QC for genotypes from Illumina Infinium arrays

Description

Perform quantile normalization of intensity data.

Usage

## S3 method for class 'normalize'
quantile(x, weights = NULL, force = FALSE, ...)

Arguments

x	a genotypes object
weights	a vector of column weights
force	re-run the normalization procedure even if attr(,"normalized") is set to TRUE
...	ignored

Details

A simple wrapper around the quantile normalization originally described in Bolstad et al. (2003), as implemented in preprocessCore::normalize.quantiles.robust().

Value

A copy of the input object, with raw intensities replaced by the normalized ones.

References

Bolstad BM et al. (2003) A comparison of normalization methods for high density oligonucleotide array data based on bias and variance. Bioinformatics 19(2): 185-193.

andrewparkermorgan/argyle documentation built on May 10, 2019, 11:08 a.m.