dot-addRegulationInformationAndFilterDEGs: .addRegulationInformationAndFilterDEGs

In bimberlabinternal/CellMembrane: A package with high-level wrappers and pipelines for single-cell RNA-seq tools

.addRegulationInformationAndFilterDEGs

Description

a helper function for PseudobulkingBarPlot to tag genes as up- or down-regulated and check for uniqueness of differential gene expression across the contrasts.

Usage

.addRegulationInformationAndFilterDEGs(
  tibble,
  logFC_threshold = 1,
  FDR_threshold = 0.05
)

Arguments

tibble	a (presumably large) tibble from dplyr containing the results of RunFilteredPseudobulkingContrasts
logFC_threshold	The minimum value for a gene's absolute value of log fold change to be considered differentially expressed.
FDR_threshold	The maximum value for a gene's FDR to be considered differentially expressed.

Value

a tibble with the uniqueness and direction of regulation for each gene stored in tibble$regulation

bimberlabinternal/CellMembrane documentation built on Oct. 16, 2024, 6:53 a.m.