SCN: SCN normalization from Cournac 2012

View source: R/Cournac_normalization.R

SCNR Documentation

SCN normalization from Cournac 2012

Description

SCN normalization from Cournac 2012

Usage

SCN(a, max.iter = 10)

Arguments

a

The matrix to be normalized. Any cols/rows that sum to 0 will be removed before normalization.

max.iter

maximum number of iterations to be performed

Details

Performs Sequential Component Normalization as described by Cournac. Coded using details in the manuscript. Cournac A, Marie-Nelly H, Marbouty M, Koszul R, Mozziconacci J. Normalization of a chromosomal contact map. BMC Genomics. 2012;13: 436. doi:10.1186/1471-2164-13-436

Value

An SCN normalized matrix

Examples

m <- matrix(rpois(100, 5), 10, 10)
SCN(m)

dozmorovlab/HiCcompare documentation built on June 30, 2023, 3:09 a.m.