View source: R/Cournac_normalization.R
SCN | R Documentation |
SCN normalization from Cournac 2012
SCN(a, max.iter = 10)
a |
The matrix to be normalized. Any cols/rows that sum to 0 will be removed before normalization. |
max.iter |
maximum number of iterations to be performed |
Performs Sequential Component Normalization as described by Cournac. Coded using details in the manuscript. Cournac A, Marie-Nelly H, Marbouty M, Koszul R, Mozziconacci J. Normalization of a chromosomal contact map. BMC Genomics. 2012;13: 436. doi:10.1186/1471-2164-13-436
An SCN normalized matrix
m <- matrix(rpois(100, 5), 10, 10)
SCN(m)
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