Reduce clone trees produced by infer.clonal.models to the core models, ie. ones that do not affect how clonal evolve and branch across samples. This function will strip off the clones that involve only one sample, any excluded nodes, and compare the trees and keep only ones that are different. Return a list of merged.trees
1 2 | trim.clone.trees(merged.trees, remove.sample.specific.clones = TRUE,
samples = NULL, seeding.aware.tree.pruning = TRUE)
|
merged.trees: |
output of infer.clonal.models()$matched$merged.trees or any list of trees produced by infer.clonal.models()$models |
remove.sample.specific.clones: |
remove clones that are found in only one sample before comparing, default=T (used when reducing merged trees. Set this to F to compare and reduce multiple samples with the same tree to one sample |
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