Description Usage Arguments Details See Also Examples
Prepare mutational landscape data for plot.landscape
. Automatically selected q-value cutoff to nominate SMGs.
1 | get.mutland(genes=NULL, mutsigcv.sig.gene.file, gene.mut.freq.file, mut.per.smp.file, gene.mut.mat.file, use.q.value=TRUE, discard.genes=c("TTN"))
|
genes |
A vector of gene symbols to be selected, if NULL automatically select SMGs. |
mutsigcv.sig.gene.file |
MutSigCV output file, often suffixed with |
gene.mut.freq.file |
Gene mutation frequency file. |
mut.per.smp.file |
Mutation per sample file. |
gene.mut.mat.file |
Gene mutation matrix file. |
use.q.value |
Use q-value in |
discard.genes |
Gene to be ignored in |
mutsigcv.sig.gene.file
is generated by MutSigCV
.
gene.mut.freq.file
, mut.per.smp.file
, gene.mut.mat.file
can be generaed by ngstk1.0 muMat
.
plot.landscape
, plot.landscape2
1 2 | # Not run
r=get.mutland(genes=NULL, "../MutSigCV/GC.WES.sig_genes.txt", "../basic_stats/WES.exonic.gene_mut_freq.txt", "../basic_stats/WES.exonic.mut_per_sample.txt", "../basic_stats/WES.exonic.gene_mut_mat.txt", F, top.k.gene=13, discard.genes="TTN")
|
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