get.mutland: Prepare data for 'plot.landscape'

Description Usage Arguments Details See Also Examples

View source: R/get.mutland.R

Description

Prepare mutational landscape data for plot.landscape. Automatically selected q-value cutoff to nominate SMGs.

Usage

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get.mutland(genes=NULL, mutsigcv.sig.gene.file, gene.mut.freq.file, mut.per.smp.file, gene.mut.mat.file, use.q.value=TRUE, discard.genes=c("TTN"))

Arguments

genes

A vector of gene symbols to be selected, if NULL automatically select SMGs.

mutsigcv.sig.gene.file

MutSigCV output file, often suffixed with *.sig_genes.txt.

gene.mut.freq.file

Gene mutation frequency file.

mut.per.smp.file

Mutation per sample file.

gene.mut.mat.file

Gene mutation matrix file.

use.q.value

Use q-value in mutsigcv.sig.gene.file, else use p-value.

discard.genes

Gene to be ignored in genes.

Details

mutsigcv.sig.gene.file is generated by MutSigCV.

gene.mut.freq.file, mut.per.smp.file, gene.mut.mat.file can be generaed by ngstk1.0 muMat.

See Also

plot.landscape, plot.landscape2

Examples

1
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# Not run
r=get.mutland(genes=NULL, "../MutSigCV/GC.WES.sig_genes.txt", "../basic_stats/WES.exonic.gene_mut_freq.txt", "../basic_stats/WES.exonic.mut_per_sample.txt", "../basic_stats/WES.exonic.gene_mut_mat.txt", F, top.k.gene=13, discard.genes="TTN")

lixiangchun/lxctk documentation built on May 21, 2019, 6:44 a.m.