landscape.data: Prepare data for 'plot.landscape'

Description Usage Arguments Details See Also Examples

View source: R/landscape.data.R

Description

Prepare mutational landscape data for plot.landscape.

Usage

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landscape.data(genes=NULL, mutsigcv.sig.gene.file, gene.mut.freq.file, mut.per.smp.file, gene.mut.mat.file, use.q.value=T, top.k.gene=12, discard.genes=c("TTN"))

Arguments

genes

A vector of gene symbols to be selected

mutsigcv.sig.gene.file

MutSigCV output file, often suffixed with *.sig_genes.txt.

gene.mut.freq.file

Gene mutation frequency file.

mut.per.smp.file

Mutation per sample file.

gene.mut.mat.file

Gene mutation matrix file.

use.q.value

Use q-value in mutsigcv.sig.gene.file, else use p-value.

top.k.gene

The top of highly mutated gene count. If genes is NULL use the top.k.gene highly mutated genes.

discard.genes

Gene to be ignored in genes.

Details

mutsigcv.sig.gene.file is generated by MutSigCV.

gene.mut.freq.file, mut.per.smp.file, gene.mut.mat.file can be generaed by ngstk1.0 muMat.

See Also

plot.landscape

Examples

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# Not run
r=landscape.data(genes=NULL, "../MutSigCV/GC.WES.sig_genes.txt", "../basic_stats/WES.exonic.gene_mut_freq.txt", "../basic_stats/WES.exonic.mut_per_sample.txt", "../basic_stats/WES.exonic.gene_mut_mat.txt", F, top.k.gene=13, discard.genes="TTN")

lixiangchun/lxctk documentation built on May 21, 2019, 6:44 a.m.