This is a suggested scoring function that collapses two informative numbers, a fold change conveying effect size and a z-score conveying significance, into a single number in a fixed range [-1, 1]
1 |
fc |
numeric. Values of fold change (e.g. 2 for 2-fold up-regualtion, 0.25 for 4-fold down-regulation). |
z |
numeric. Values of z-score |
fc.thresh |
numeric vector of length two. Should hold lower and upper thresholds for interesting fold-changes. Values of fc below lower threshold will receive score 0. Values above upper threshold will receive score 1. Intermediate values follow linear interpolation. |
z.thresh |
numeric vector of length two. Analogous to fc.thresh, but here thresholds applied to z score. |
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