diffPath: To find different enriched pathway between two group cells

In yingyonghui/CommPath:

To find different enriched pathway between two group cells

Description

To find different enriched pathway between two group cells

Usage

diffPath(
  object,
  select.ident.1,
  select.ident.2 = NULL,
  method = "t.test",
  only.posi = FALSE,
  only.sig = FALSE
)

Arguments

object	CommPath object
select.ident.1	Identity class to define cells for group 1
select.ident.2	Identity class to define cells for group 2 for comparison; if 'NULL', use all other cells for comparison
method	Method used for differential enrichment analysis, either 't.test' of 'wilcox.test'
only.posi	only save the information of pathways showing up regulation
only.sig	only save the information of pathways showing significant differences

Value

Data frame including the statistic result comparing the pathway enrichment sorces between group 1 and group 2, the significant recetor and ligand of group 1 in the pathways, and the corresponding up stream identity class which interact with group 1 by releasing specific ligand

yingyonghui/CommPath documentation built on June 15, 2025, 6:29 a.m.