normOLIN: Normalise a cDNA Microarray Object

In maigesPack: Functions to handle cDNA microarray data, including several methods of data analysis

Description

This function loads a maigesRaw object and normalise it using methods OLIN or OSLIM.

Usage

normOLIN(obj=NULL, ...)

Arguments

obj	object of type maigesRaw to be normalised.
...	additional parameters for function olin.

Details

This function for normalisation is entirely based on function olin from OLIN package. This function implements the methods OLIN and OSLIM, proposed by Futschich and Crompton (2004). See help page for this function to discover how to set the parameters.

Value

This function returns a maiges object.

Author(s)

Gustavo H. Esteves <[e-mail]>

References

Futschik, M. and Crompton, T. Model selection and efficiency testing for normalization of cDNA microarray data, Genome Biology, 5, R60, 2004 (http://genomebiology.com/2004/5/8/R60).

See Also

olin from OLIN package.

Examples

## Loading the dataset
data(gastro)

## Doing the OLIN normalization. Pay attention because, this methods are
## very time consuming!
## Not run: 
gastro.norm = normOLIN(gastro.raw2) ## Without scale adjustment

gastro.norm = normOLIN(gastro.raw2, OSLIN=TRUE) ## With scale adj

## End(Not run)

maigesPack documentation built on Nov. 8, 2020, 6:23 p.m.