Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.
|Author||Liye He <email@example.com>, Jing Tang <firstname.lastname@example.org>|
|Date of publication||None|
|Maintainer||Liye He <email@example.com>|
|License||Artistic License 2.0|
BaselineCorrectionSD: Baseline correction for the dose-response matrix of drug...
Bliss: Synergy score based on Bliss model
CalculateSynergy: Calculate the synergy scores for drug combinations
FittingSingleDrug: Fitting single drug dose-response curve
HSA: HSA synergy score based on highest single agent (HSA) model
Loewe: Delta synergy score based on Loewe model
mathews_screening_data: A high-throughput drug combination screening data
PlotDoseResponse: Visualize the drug combination dose-response data
PlotSynergy: Drug interaction landscape
ReshapeData: Transform the response data from the data frame format to...
ZIP: Delta synergy score based on zero interaction potency (ZIP)...