Description Usage Arguments Details Value See Also
View source: R/classPKNCAdose.R
Create a PKNCAdose object
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data 
A data frame with time and the groups defined in

... 
Ignored. 
formula 
The formula defining the

route 
Define the route of administration. The value may be
either a column name from the 
rate, duration 
(optional) for 
time.nominal 
(optional) The name of the nominal time column
(if the main time variable is actual time. The 
exclude 
(optional) The name of a column with concentrations to
exclude from calculations and summarization. If given, the column
should have values of 
The formula
for a PKNCAdose
object can be
given three ways: onesided (missing left side), onesided (missing
right side), or twosided. Each of the three ways can be given
with or without groups. When given onesided missing the left
side, the left side can either be omitted or can be given as a
period (.
): ~timetreatment+subject
and
.~timetreatment+subject
are identical, and doserelated NCA
parameters will all be reported as not calculable (for example,
clearance). When given onesided missing the right side, the right
side must be specified as a period (.
):
dose~.treatment+subject
, and only a single row may be given
per group. When the right side is missing, PKNCA assumes that the
same dose is given in every interval. When given as a twosided
formula
A PKNCAconc object that can be used for automated NCA.
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