pk.nca.interval | R Documentation |
For one subject/time range, compute all available PK parameters. All
the internal options should be set by PKNCA.options
prior to running. The only part that changes with a call to this
function is the conc
entration and time
.
pk.nca.interval(
conc,
time,
volume,
duration.conc,
dose,
time.dose,
duration.dose,
route,
conc.group = NULL,
time.group = NULL,
volume.group = NULL,
duration.conc.group = NULL,
dose.group = NULL,
time.dose.group = NULL,
duration.dose.group = NULL,
route.group = NULL,
impute_method = NA_character_,
include_half.life = NULL,
exclude_half.life = NULL,
subject,
sparse,
interval,
options = list()
)
conc, conc.group |
Concentration measured for the current interval or all data for the group |
time, time.group |
Time of concentration measurement for the current interval or all data for the group |
volume, volume.group |
The volume (or mass) of the concentration measurement for the current interval or all data for the group (typically for urine and fecal measurements) |
duration.conc, duration.conc.group |
The duration of the concentration measurement for the current interval or all data for the group (typically for urine and fecal measurements) |
dose, dose.group |
Dose amount (may be a scalar or vector) for the current interval or all data for the group |
time.dose, time.dose.group |
Time of the dose for the current
interval or all data for the group (must be the same length as
|
duration.dose, duration.dose.group |
The duration of the dose administration for the current interval or all data for the group (typically zero for extravascular and intravascular bolus and nonzero for intravascular infusion) |
route, route.group |
The route of dosing for the current interval or all data for the group |
impute_method |
The method to use for imputation as a character string |
include_half.life |
An optional boolean vector of the concentration measurements to include in the half-life calculation. If given, no half-life point selection will occur. |
exclude_half.life |
An optional boolean vector of the concentration measurements to exclude from the half-life calculation. |
subject |
Subject identifiers (used for sparse calculations) |
sparse |
Should only sparse calculations be performed (TRUE) or only dense calculations (FALSE)? |
interval |
One row of an interval definition (see
|
options |
List of changes to the default
|
A data frame with the start and end time along with all PK
parameters for the interval
check.interval.specification
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