time_calc: Times relative to an event (typically dosing)

In PKNCA: Perform Pharmacokinetic Non-Compartmental Analysis

Times relative to an event (typically dosing)

Description

Times relative to an event (typically dosing)

Usage

time_calc(time_event, time_obs, units = NULL)

Arguments

time_event	A vector of times for events
time_obs	A vector of times for observations
units	Passed to base::as.numeric.difftime()

Value

A data.frame with columns for:

event_number_before

The index of time_event that is the last one before time_obs or NA if none are before.

event_number_after

The index of time_event that is the first one after time_obs or NA if none are after.

time_before

The minimum time that the current time_obs is before a time_event, 0 if at least one time_obs == time_event.

time_after

The minimum time that the current time_obs is after a time_event, 0 if at least one time_obs == time_event.

time_after_first

The time after the first event (may be negative or positive).

time_after and time_before are calculated if they are at the same time as a dose, they equal zero, and otherwise, they are calculated relative to the dose number in the ⁠event_number_*⁠ columns.

PKNCA documentation built on Aug. 21, 2025, 6 p.m.