time_calc: Times relative to an event (typically dosing)

In PKNCA: Perform Pharmacokinetic Non-Compartmental Analysis

Times relative to an event (typically dosing)

Description

Times relative to an event (typically dosing)

Usage

time_calc(time_event, time_obs, units = NULL)

Arguments

time_event	A vector of times for events
time_obs	A vector of times for observations
units	Passed to 'base::as.numeric.difftime()'

Value

A data.frame with columns for:

• event_number_beforeThe index of 'time_event' that is the last one before 'time_obs' or 'NA' if none are before.

• event_number_afterThe index of 'time_event' that is the first one after 'time_obs' or 'NA' if none are after.

• time_beforeThe minimum time that the current 'time_obs' is before a 'time_event', 0 if at least one 'time_obs == time_event'.

• time_afterThe minimum time that the current 'time_obs' is after a 'time_event', 0 if at least one 'time_obs == time_event'.

• time_after_firstThe time after the first event (may be negative or positive).

'time_after' and 'time_before' are calculated if they are at the same time as a dose, they equal zero, and otherwise, they are calculated relative to the dose number in the 'event_number_*' columns.

PKNCA documentation built on April 30, 2023, 1:08 a.m.