Power and Sample Size Based on Two One-Sided t-Tests (TOST) for (Bio)Equivalence Studies

bib.CL | Design matrices of period balanced incomplete block designs |

CI.BE | 1-2*alpha confidence interval given point estimate, CV and n |

CI.RatioF | 1-2*alpha Fieller confidence interval given point est., CV... |

CV2se | Helper functions |

CVCL | Confidence limits of a CV for log-normal data |

CVfromCI | CV from a given Confidence interval |

CVp2CV | Decompose CV(T) and CV(R) from 'pooled' CV of T/R |

CVpooled | Pooled CV from several studies |

CVwRfromU | CVwR from the upper expanded limit (ABEL) |

data_2x2 | Sample Size Tables for the Classical 2x2 Crossover Design |

data_2x2x3 | Sample Size Tables for the 2x2x3 Replicate Crossover Design |

data_2x4x4 | Sample Size Tables for the 2x4x4 Replicate Crossover Design |

data_parallel | Sample Size Tables for the Parallel Group Design |

exppower.noninf | Expected power of the non-inferiority test |

exppower.TOST | Expected power of the TOST procedure |

expsampleN.noninf | Sample size based on expected power for the non-inferiority... |

expsampleN.TOST | Sample size based on expected power |

known.designs | Show the 'known' designs |

OwensQ | Owen's Q-function |

OwensQOwen | Owen's Q-function via repeated integration by parts |

OwensT | Owen's T-function |

pa.ABE | Power analysis for average bioequivalence (ABE) |

pa.NTIDFDA | Power analysis for scaled ABE for NTIDs according to FDA |

pa.scABE | Power analysis for scaled average bioequivalence (scABE) |

power.2TOST | Power for two simultaneous TOST procedures |

power.dp | Power of dose-proportionality studies evaluated via Power... |

power.HVNTID | (Empirical) Power for BE decision via FDA method for highly... |

power.noninf | Power of the one-sided non-inferiority t-test |

power.NTIDFDA | (Empirical) Power for BE decision via FDA method for NTIDs |

power.RatioF | Power for equivalence of the ratio of two means with... |

power.RSABE | (Empirical) Power for BE decision via linearized scaled ABE... |

power.scABEL | (Empirical) Power of BE decision via scaled (widened) BE... |

power.scABEL.sdsims | (Empirical) Power of BE decision via scaled (widened) BE... |

power.TOST | Power of the classical TOST procedure |

power.TOST.sim | Power of the TOST procedure obtained via simulations |

pvalue.TOST | p-value(s) of the TOST procedure |

reg_const | Constructor of an object with class 'regSet' containing the... |

sampleN.2TOST | Sample size based on power of 2 TOSTs |

sampleN.dp | Sample size estimation of dose-proportionality studies... |

sampleN.HVNTID | Sample size estimation for BE decision via FDA method for... |

sampleN.noninf | Sample size for the non-inferiority t-test |

sampleN.NTIDFDA | Sample size estimation for BE decision via FDA method for... |

sampleN.RatioF | Sample size for equivalence of the ratio of two means with... |

sampleN.RSABE | Sample size estimation for BE decision via linearized scaled... |

sampleN.scABEL | Sample size estimation for BE decision via scaled (widened)... |

sampleN.scABEL.ad | Sample size estimation for ABEL and iteratively adjusted... |

sampleN.TOST | Sample size based on power of TOST |

scABEL | Scaled (widened) BE Acceptance Limits |

scABEL.ad | Iteratively adjusted alpha for ABEL |

type1error.2TOST | Type I error rate for two simultaneous TOST procedures |

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