data_2x2x3: Sample Size Tables for the 2x2x3 Replicate Crossover Design

In PowerTOST: Power and Sample Size for (Bio)Equivalence Studies

Sample Size Tables for the 2x2x3 Replicate Crossover Design

Description

These data.frames give sample size tables calculated with sampleN.TOST() for the 2×2×3 replicate crossover design (2-treatment 2-sequence 3-period design.

Details

The data.frames can be accessed by their names.

data.frame	Description
ct9.6.2	Additive model, theta1=--0.2, theta2=+0.2 (BE limits 0.80 -- 1.20)
	approximate power via shifted non-central t-distribution
ct9.6.6	Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1)
	approximate power via shifted non-central t-distribution

Attention! CV is se (standard error) of residuals.

Note

Scripts for creation of these data.frames can be found in the /tests sub-directory of the package.
Comparing the results of these scripts to the corresponding data.frames can be used for validation purposes.

Author(s)

PowerTOST

Source

data.frame	Origin	Details
ct9.6.2	Chow & Liu	Table 9.6.2 (p 292)
ct9.6.6	Chow & Liu	Table 9.6.6 (p 293)

References

Chow SC, Liu JP. Design and Analysis of Bioavailability and Bioequivalence Studies. Boca Raton: CRC Press; 3^rd edition 2009.

Examples

ct9.6.2
ct9.6.6

PowerTOST documentation built on March 18, 2022, 5:47 p.m.