Description Details Note Author(s) Examples

These data.frames give sample size tables calculated with
`sampleN.TOST()`

for the parallel group design (2 groups).

The data.frames can be accessed by their names.

ctSJ.VIII.10 is Table VIII, column ‘level of bioequivalence 10%’ from

Julious SA. *Tutorial in Biostatistics. Sample sizes for clinical trials with Normal data.*

Stat Med. 2004;23(12):1921–86. doi: 10.1002/sim.1783

Multiplicative model, theta1=0.9, theta2=1.1111 (1/theta1), target power=90%,

power approximate via non-central *t*-distribution.

Attention! Julious gives sample size per group.

ctSJ.VIII.20 is Table VIII from the same source

column ‘level of bioequivalence 20%’

Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1), target power=90%,

power approximate via non-central *t*.

ctCW.III is Table III from

Chow SC, Wang H. *On Sample Size Calculation in Bioequivalence Trials*

J Pharmacokinet Pharmacodyn. 2001. 28(2):155–69.

Additive model, theta1=–0.2, theta2=+0.2 (BE limits 0.80 – 1.20), exact.

Seems the last reference is not very reliable (compare to the Table in the paper).

Scripts for creation of these data.frames can be found in the \test
sub-directory of the package.

Comparing the results of these scripts to the corresponding data.frames can
be used for validation purposes.

PowerTOST

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