Power and Sample Size for (Bio)Equivalence Studies

Vignettes

- README.md
- Average Bioequivalence"
- Dose-Proportionality"
- Main Vignette"
- Non-Inferiority"
- Power Analysis"
- Reference-Scaled Average Bioequivalence"

213

69

56

**bib.CL:**Design matrices of period balanced incomplete block designs**CI.BE:**1-2*alpha confidence interval given point estimate, CV, and n**CI.RatioF:**1-2*alpha Fieller CI given point estimate, CV (, CVb) and n**CV2se:**Helper functions**CVCL:**Confidence limits of a CV for log-normal data**CVfromCI:**CV from a given Confidence interval**CVp2CV:**Decompose CV(T) and CV(R) from 'pooled' CV of T/R**CVpooled:**Pooled CV from several studies**CVwRfromU:**CVwR from the upper expanded limit (ABEL)**data_2x2:**Sample Size Tables for the Classical 2x2 Crossover Design**data_2x2x3:**Sample Size Tables for the 2x2x3 Replicate Crossover Design**data_2x4x4:**Sample Size Tables for the 2x4x4 Replicate Crossover Design**data_parallel:**Sample Size Tables for the Parallel Group Design**defunct:**Removed functions in PowerTOST**deprecated:**Deprecated functions in PowerTOST**exppower.noninf:**Expected power of the non-inferiority test**exppower.TOST:**Expected power of the TOST procedure**expsampleN.noninf:**Sample size based on expected power for the non-inferiority...**expsampleN.TOST:**Sample size based on expected power**known.designs:**Show the 'known' designs**OwensQ:**Owen's Q-function**OwensQOwen:**Owen's Q-function via repeated integration by parts**OwensT:**Owen's T-function**pa.ABE:**Power analysis for average bioequivalence (ABE)**pa.NTID:**Power analysis for scaled ABE for NTIDs**pa.scABE:**Power analysis for scaled average bioequivalence (scABE)**power.2TOST:**Power for two simultaneous TOST procedures**power.dp:**Power of dose-proportionality studies evaluated via Power...**power.HVNTID:**(Empirical) Power for BE decision via FDA method for highly...**power.noninf:**Power of the one-sided non-inferiority t-test**power.NTID:**(Empirical) Power for BE decision via FDA method for NTIDs**power.RatioF:**Power for equivalence of the ratio of two means with...**power.RSABE:**(Empirical) Power for BE decision via linearized scaled ABE...**power.RSABE2L.sdsims:**(Empirical) Power of BE Decision via Reference Scaled ABE**power.scABEL:**(Empirical) Power of BE decision via scaled (widened) BE...**power.scABEL.sdsims:**(Empirical) Power of BE decision via scaled (widened) BE...**power.TOST:**Power of the classical TOST procedure**power.TOST.sds:**Power calculation of the BE decision with models...**power.TOST.sim:**Power of the TOST procedure obtained via simulations**pvalue.TOST:**p-value(s) of the TOST procedure**reg_const:**Constructor of an object with class 'regSet' containing the...**sampleN.2TOST:**Sample size based on power of two TOSTs**sampleN.dp:**Sample size estimation of dose-proportionality studies...**sampleN.HVNTID:**Sample size estimation for BE decision via FDA method for...**sampleN.noninf:**Sample size for the non-inferiority t-test**sampleN.NTID:**Sample size estimation for BE decision via the FDA's method...**sampleN.RatioF:**Sample size for equivalence of the ratio of two means with...**sampleN.RSABE:**Sample size estimation for BE decision via linearized scaled...**sampleN.RSABE2L.sdsims:**Sample size estimation for BE Decision via Reference Scaled...**sampleN.scABEL:**Sample size estimation for BE decision via scaled (expanded)...**Browse all...**

deprecated | R Documentation |

Details about deprecated functions in PowerTOST.

The functions `power.NTIDFDA`

, `sampleN.NTIDFDA`

, and `pa.NTIDFDA`

were deprecated in version 1.5.4 and will be removed future versions.

`power.NTID`

, `sampleN.NTID`

, `pa.NTIDFDA`

for the new functions.

What can we improve?

Embedding an R snippet on your website

Add the following code to your website.

For more information on customizing the embed code, read Embedding Snippets.

Close