Cellular_preclustering: Preclustering method

Description Usage Arguments Value

View source: R/FlashQC.R

Description

This method clusters mutations based on the probability that they are from the same distribution. It first computes the zscore associated with a normalized number of alternative reads and depth. The "normalized" number of reads is the number of alternative reads expected if the mutation was at a single copy in a diploid genome.

Usage

1
Cellular_preclustering(Schrod_cells)

Arguments

Schrod_cells

The classic output from Schrodinger function

Value

returns a list with:

similarityMatrix

The matrix of probabilities

distance

The dissimilarity matrix

tree

The tree obtained by hierachical clustering of the dissimilarity matrix using "ward.D2" method


QuantumClone documentation built on May 2, 2019, 3:03 a.m.