Optimization of clone positions and proportion of mutations in each clone.

1 2 |

`Schrod` |
A list of dataframes (one for each sample), generated by the Patient_schrodinger_cellularities() function. |

`nclust` |
Number of clones to look for (mandatory if prior_center or prior_weight are null) |

`prior_center` |
Clone coordinates (from another analysis) to be used |

`prior_weight` |
Prior on the fraction of mutation in each clone |

`contamination` |
Numeric vector with the fraction of normal cells contaminating the sample |

`epsilon` |
Stopping condition for the algorithm: what is the minimal tolerated difference of position or weighted between two steps |

`optim` |
use L-BFS-G optimization from R ("default"), or from optimx ("optimx") |

Questions? Problems? Suggestions? Tweet to @rdrrHQ or email at ian@mutexlabs.com.

All documentation is copyright its authors; we didn't write any of that.