View source: R/analyze_gene_drug_response.R
analyze_gene_drug_response_asso | R Documentation |
Analyze partial correlation of gene-drug association after controlling for tissue average expression.
analyze_gene_drug_response_asso(gene_list, combine = FALSE)
gene_list |
a gene symbol list. |
combine |
if |
a data.frame
If combine
is TRUE
, genes are combined as signature
.
mean.diff
and median.diff
indicate mean and median of
normalized expression difference between High IC50 cells and Low IC50 cells.
The cutoff between High and Low are median IC50.
## Not run: analyze_gene_drug_response_asso("TP53") analyze_gene_drug_response_asso(c("TP53", "KRAS")) analyze_gene_drug_response_asso(c("TP53", "KRAS"), combine = TRUE) # Visualization vis_gene_drug_response_asso("TP53") ## End(Not run)
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