Description Usage Arguments Details Value Author(s) References See Also Examples

Reads data file from Cochrane Intervention review created with RevMan 5 and creates a data frame from it.

1 2 |

`file` |
The name of a file to read data values from. |

`sep` |
The field separator character. Values on each line of the file are separated by this character. The comma is the default field separator character in RevMan 5. |

`quote` |
The set of quoting characters. In RevMan 5 a "\"" is the default quoting character. |

`title` |
Title of Cochrane review. |

`numbers.in.labels` |
A logical indicating whether comparision
number and outcome number should be printed at the beginning of the
comparison (argument |

Review Manager 5 (RevMan 5) is the current software used for preparing and maintaining Cochrane Reviews (http://community.cochrane.org/tools/review-production-tools/revman-5). RevMan 5 includes the ability to write Systematic reviews of interventions, Diagnostic test accuracy reviews, Methodology reviews and Overviews of reviews.

This function provides the ability to read a data file from a Cochrane Intervention review created with RevMan 5; a data frame is created from it. Cochrane Intervention reviews are based on the comparison of two interventions.

In order to generate a data analysis file in RevMan 5 use the
following Menu points: `"File"`

- `"Export"`

- ```
"Data
and analyses"
```

. It is mandatory to include the following fields in
the exported data file by selecting them with the mouse cursor in
the Export Analysis Data Wizard: (i) Comparison Number, (ii) Outcome
Number, (iii) Subgroup Number. When these fields are not selected a
corresponding error message will be printed in R. It is recommended
to include all fields in the exported data file except for the last
field "Risk of bias tables". For example, in order to redo the
meta-analysis in R for the RevMan 5 data type ```
"O-E and
Variance"
```

the fields `"O-E"`

and `"Variance"`

have to be
selected in the Export Analysis Data Wizard. If the last field "Risk
of bias tables" is selected the import in R fails with an error
message "line X did not have Y elements".

By default in RevMan 5, the name of the exported data file is the
title of the Cochrane Review. Accordingly, information on the title is
extracted from the name of the exported data file (argument:
`file`

) if argument `title`

is missing (default).

Each respective meta-analysis for arguments `event.e.pooled`

–
`df.pooled`

is defined by values for `"comp.no"`

and
`"outcome.no"`

, and `"grp.no"`

.

A data frame containing the following components:

`comp.no` |
Comparison number. |

`outcome.no` |
Outcome number. |

`group.no` |
Group number. |

`studlab` |
Study label. |

`year` |
Year of publication. |

`event.e` |
Number of events in experimental group. |

`n.e` |
Number of observations in experimental group. |

`event.c` |
Number of events in control group. |

`n.c` |
Number of observations in control group. |

`mean.e` |
Estimated mean in experimental group. |

`sd.e` |
Standard deviation in experimental group. |

`mean.c` |
Estimated mean in control group. |

`sd.c` |
Standard deviation in control group. |

`O.E` |
Observed minus expected (IPD analysis). |

`V` |
Variance of |

`TE, seTE` |
Estimated treatment effect and standard error of individual studies. |

`lower, upper` |
Lower and upper limit of 95% confidence interval for treatment effect in individual studies. |

`weight` |
Weight of individual studies (according to meta-analytical method used in respective meta-analysis - see below for details). |

`order` |
Ordering of studies. |

`grplab` |
Group label. |

`type` |
Type of outcome. D = dichotomous, C = continuous, P = IPD. |

`method` |
A character string indicating which method has been used
for pooling of studies. One of |

`sm` |
A character string indicating which summary measure has been used for pooling of studies. |

`model` |
A character string indicating which meta-analytical model
has been used (either |

`comb.fixed` |
A logical indicating whether fixed effect meta-analysis has been used in respective meta-analysis (see below for details). |

`comb.random` |
A logical indicating whether random effects meta-analysis has been used in respective meta-analysis (see below for details). |

`outclab` |
Outcome label. |

`k` |
Total number of studies combined in respective meta-analysis). |

`event.e.pooled` |
Number of events in experimental group in respective meta-analysis (see below for details). |

`n.e.pooled` |
Number of observations in experimental group in respective meta-analysis (see below for details). |

`event.c.pooled` |
Number of events in control group in respective meta-analysis (see below for details). |

`n.c.pooled` |
Number of observations in control group in respective meta-analysis (see below for details). |

`TE.pooled` |
Estimated treatment effect in respective meta-analysis (see below for details). |

`lower, upper` |
Lower and upper limit of 95% confidence interval for treatment effect in respective meta-analysis (see below for details). |

`weight.pooled` |
Total weight in respective meta-analysis (see below for details). |

`Z.pooled` |
Z-score for test of overall treatment effect in respective meta-analysis (see below for details). |

`pval.pooled` |
P-value for test of overall treatment effect in respective meta-analysis (see below for details). |

`Q` |
Heterogeneity statistic Q in respective meta-analysis (see below for details). |

`pval.Q` |
P-value of heterogeneity statistic Q in respective meta-analysis (see below for details). |

`I2` |
Heterogeneity statistic I2 in respective meta-analysis (see below for details). |

`tau2` |
Between-study variance (moment estimator of DerSimonian-Laird) in respective meta-analysis. |

`Q.w` |
Heterogeneity statistic Q within groups in respective meta-analysis (see below for details). |

`pval.Q.w` |
P-value of heterogeneity statistic Q within groups in respective meta-analysis (see below for details). |

`I2.w` |
Heterogeneity statistic I2 within groups in respective meta-analysis (see below for details). |

`label.e` |
Label for experimental group. |

`label.c` |
Label for control group. |

`label.left` |
Graph label on left side of forest plot. |

`label.right` |
Graph label on right side of forest plot. |

`RR.cochrane` |
A logical indicating if 2* |

`complab` |
Comparison label. |

Guido Schwarzer sc@imbi.uni-freiburg.de

*Review Manager (RevMan)* [Computer program]. Version
5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane
Collaboration, 2014.

`metabin`

, `metacont`

, `metagen`

, `metacr`

1 2 3 4 5 6 7 8 9 10 11 12 13 14 | ```
# Locate export data file "Fleiss93_CR.csv"
# in sub-directory of package "meta"
#
filename <- system.file("data/Fleiss93_CR.csv.gz", package = "meta")
#
Fleiss93_CR <- read.rm5(filename)
# Same result as R command example(Fleiss93):
#
metacr(Fleiss93_CR)
# Same result as R command example(Fleiss93cont):
#
metacr(Fleiss93_CR, 1, 2)
``` |

```
Loading 'meta' package (version 4.8-2).
Type 'help(meta)' for a brief overview.
Review: Fleiss93_CR.csv.gz
Comparison: 1 Examples from Fleiss (1993)
Outcome: 1.1 Aspirin for Preventing Death after Myocardial Infarction
OR 95%-CI %W(fixed)
MRC-1 0.7197 [0.4890; 1.0593] 3.2
CDP 0.6808 [0.4574; 1.0132] 3.1
MRC-2 0.8029 [0.6065; 1.0629] 5.7
GASP 0.8007 [0.4863; 1.3186] 1.8
PARIS 0.7981 [0.5526; 1.1529] 3.2
AMIS 1.1327 [0.9347; 1.3728] 10.2
ISIS-2 0.8950 [0.8294; 0.9657] 72.9
Number of studies combined: k = 7
OR 95%-CI z p-value
Fixed effect model 0.8969 [0.8405; 0.9570] -3.29 0.0010
Quantifying heterogeneity:
tau^2 = 0.0096; H = 1.29 [1.00; 1.99]; I^2 = 39.7% [0.0%; 74.6%]
Test of heterogeneity:
Q d.f. p-value
9.95 6 0.1269
Details on meta-analytical method:
- Mantel-Haenszel method
Review: Fleiss93_CR.csv.gz
Comparison: 1 Examples from Fleiss (1993)
Outcome: 1.2 Mental Health Treatment versus Control
MD 95%-CI %W(fixed)
Davis -1.5000 [-4.7855; 1.7855] 2.8
Florell -1.2000 [-2.0837; -0.3163] 38.6
Gruen -2.4000 [-6.1078; 1.3078] 2.2
Hart 0.2000 [-0.7718; 1.1718] 31.9
Wilson -0.8800 [-1.9900; 0.2300] 24.5
Number of studies combined: k = 5
MD 95%-CI z p-value
Fixed effect model -0.7094 [-1.2585; -0.1603] -2.53 0.0113
Quantifying heterogeneity:
tau^2 = 0.1894; H = 1.19 [1.00; 1.91]; I^2 = 29.3% [0.0%; 72.6%]
Test of heterogeneity:
Q d.f. p-value
5.66 4 0.2260
Details on meta-analytical method:
- Inverse variance method
```

meta documentation built on Aug. 12, 2017, 1:02 a.m.

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