SpADEGenes: 75 DE genes analysis results from LIMMA.

Description Usage Format Details Source Examples

Description

The example data provided in our package are transcriptomic profiles of MD-DCs from 9 patients with AS and 10 healthy controls. DE gene statistics group 75 genes identified by LIMMA. Samples description is also provided.

Usage

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data("SpADEGenes")

Format

A data frame with 75 observations on the following 5 variables.

GeneSymbol

HGNC gene symbol

EnsemblId

Gene Ensembl ID

P.Value

Given by LIMMA

Fold.Change

Given by LIMMA

logFC

log2(Fold.Change)

Details

This matrix groups the fold changes of p-values given by LIMMA for each gene, between patients and controls adjusted for all LPS time stimulations.

Source

Talpin, A. et al. Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression. Arthritis Res. Ther. 16, 417 (2014).

Examples

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