germlineOutliers: Identify genomic regions with outlier preprocess read depth...

View source: R/germlineOutliers.R

germlineOutliersR Documentation

Identify genomic regions with outlier preprocess read depth estimates from the lymphoblast cell lines

Description

For each 1kb bin along the genome, we assess whether two or more ovarian samples have a preprocessed read depth estimate that is more than NMADs from zero.

Usage

germlineOutliers(pviews, NMAD = 5)

Arguments

pviews

a PreprocessViews2 object

NMAD

a length-one numeric vector indicating the number of mads from zero

Details

REFACTOR: Each major directory in the DataPaths should have a final subdirectory with a views object.

Value

a GRanges object of the reduced outlier genomic intervals


cancer-genomics/trellis documentation built on Aug. 20, 2024, 5:48 p.m.