ExtractTopFeaturesST: Extract top features

Description Usage Arguments See Also

View source: R/topic_functions.R

Description

Extract top features

Usage

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ExtractTopFeaturesST(object, top_features = 1000, method = "poisson",
  options = "min", shared = FALSE)

Arguments

object

Object of class spaceST.

method

The underlying model assumed for KL divergence measurement. Two choices considered are "bernoulli" and "poisson". Default: poisson.

shared

if TRUE, then we report genes that can be highly expressed in more than one cluster. Else, we stick to only those genes that are highest expressed only in a specific cluster.

top.features

The top features in each cluster k that are selected based on the feature's ability to distinguish cluster k from cluster 1, <e2><80><a6>, K for all cluster k < l. Default: 1000.

option

if "min", for each cluster k, we select features that maximize the minimum KL divergence of cluster k against all other clusters for each feature. If "max", we select features that maximize the maximum KL divergence of cluster k against all other clusters for each feature.

See Also

ExtractTopFeatures


ludvigla/spaceST documentation built on May 29, 2019, 3:43 a.m.