This page shows a barcode plot as ouput by limma's [1] barcodeplot()
function, building on the work of Subramanian et al [2]. Please cite both if you use these plots in a publication.
Controls for this page are simple:
This plot shows where members of a gene set appear in the overall list of genes ranked by fold change between a pair of conditions. Where gene sets show strong up- or down- regulation, you expect to see 'bunching up' of its members at one extreme or the other of this ranking. This is useful to make a visual check of a gene set indicated by an FDR or a p value, and may enable you to decide how interesting a result is.
The FDR is annotated to the plot (where available).
By way of further illustration, a table is provided showing contrast details for the gene set at hand. This should enble you to chase down the origins of a significant result from gene set analysis.
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