distance: Two level shrinkage of distance matrix based on nearest...

In reggenlab/UniPath: UniPath provides robust statistical methods to represent every single cell using pathway and gene-set enrichment scores. It can be used with both single cell RNA-seq and single cell ATAC-seq profile with scalability for atlas scale data-sets. Unipath comes with several features like psuedo-temporal ordering using pathway scores and unconventional way of enumerating differences between two cell populations.

Description

Two level shrinkage of distance matrix based on nearest neighbour indices and belongingness of cells to same class

Usage

distance(dist, class, clusters)

Arguments

dist	Distance matrix used for hierarchal clustering
class	Matrix with number of times cells in same class have top k neighbors in other classes
clusters	clusters obtained from hierarchal clustering

Value

shrinked distance matrix

Examples

distance()

reggenlab/UniPath documentation built on Nov. 26, 2020, 8:09 a.m.