genkme: Internal functions for genotype-based normalization metrics

View source: R/genkme.R

genkmeR Documentation

Internal functions for genotype-based normalization metrics

Description

genkme - genotype calling with 1d k-means

genkus - apply genkme to available SNPs

getsnp - grep the rs-numbered probes

gcose - calculate between-sample SNP standard error

gcoms - calculate between-sample SNP mean-squared deviation

Usage

genkme(y, peaks = c(0.2, 0.5, 0.8))

Arguments

y

a vector or matrix of numeric values (betas, between 0 and 1)

peaks

initial values for cluster positions

Details

see genki

Value

see genki

Author(s)

Leonard.Schalkwyk@kcl.ac.uk

References

Pidsley R, Wong CCY, Volta M, Lunnon K, Mill J, Schalkwyk LC: A data-driven approach to preprocessing Illumina 450K methylation array data (submitted)


schalkwyk/wateRmelon documentation built on Aug. 13, 2024, 9:52 a.m.