calculate_diff_exp_binom: Performs differential expression analysis

In smaegol/nanotail: Analysis and visualisation of Nanopolish-based polyA lengths estimations

Performs differential expression analysis

Description

Uses counts for each identified transcript to calculate differential expression between specified groups. This function is a wrapper for binomTest from edgeR package

Usage

calculate_diff_exp_binom(
  polya_data,
  grouping_factor = NA,
  condition1 = NA,
  condition2 = NA,
  alpha = 0.05,
  summarized_input = FALSE
)

Arguments

polya_data	polya_data tibble
grouping_factor	name of column containing factor with groups for comparison
condition1	first condition to compare
condition2	second condition to compare
alpha	threshold for a pvalue, to treat the result as significant (default = 0.05)
summarized_input	is input table already summarized?

Value

a tibble with differential expression results

See Also

binomTest

smaegol/nanotail documentation built on June 29, 2024, 12:35 a.m.