getPathwaysFromGenesAndCondition: Get pathways connected to genes which are differentially...

Description Usage Arguments Value Author(s) Examples

View source: R/AtlasRDF.R

Description

Get list of pathway names that are connected to genes (via proteins which are encoded for by those genes) and which are reported as differentially expressed under a specified condition. The condition is specified as an ontology URI.

Usage

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    getPathwaysFromGenesAndCondition(condition, endpoint = "http://www.ebi.ac.uk/rdf/services/atlas/sparql")

Arguments

condition

URI of a condition based on the EFO ontology class.

endpoint

The location of the SPARQL endpoint - default value is live Atlas endpoint

Value

Returns a data frame with the following:

pathwayname

The name of the pathway

pathway

The URI identifier of the pathway

expressionvalue

The gene and expression for the pathway

pvalue

p-value of the differential expression of the gene for this pathway in this condition

Author(s)

James Malone, Simon Jupp

Examples

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    ###get pathways connected to genes which are differentially expressed for HeLa (efo:EFO_00011185)
    #getPathwaysFromGenesAndCondition("efo:EFO_0001185")
    

AtlasRDF documentation built on Nov. 17, 2017, 9:33 a.m.