MAGeCKFlute: Integrative analysis pipeline for pooled CRISPR functional genetic screens

MAGeCKFlute is designed to surporting downstream analysis, utilizing the gene summary data provided through MAGeCK or MAGeCK-VISPR. Quality control, normalization, and screen hit identification for CRISPR screen data are performed in pipeline. Identified hits within the pipeline are categorized based on experimental design, and are subsequently interpreted by functional enrichment analysis.

Package details

AuthorWubing Zhang, Feizhen Wu, Binbin Wang
Bioconductor views BatchEffect CRISPR FunctionalGenomics GeneSetEnrichment ImmunoOncology Normalization Pathways QualityControl Software Visualization
MaintainerWubing Zhang<[email protected]>
LicenseGPL (>=3)
Package repositoryView on Bioconductor
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MAGeCKFlute documentation built on Aug. 10, 2019, 2 a.m.