Description Usage Arguments Value Author(s) See Also Examples
View source: R/normInteraction.R
Normalize a square matrix of biological interactions according to the number of possible interactions between each biological complex.
1 | normInteraction(data, genename, interactome)
|
data |
Square Matrix of biological complexes that shares one or more genes(proteins) |
genename |
Character vector of the gene names that possibly create interactions between complexes |
interactome |
Adjacency matrix where row are genes and
columns are cellular organizational units. Each entry has
value 0 or 1, for absence or presence of a gene in a complex, e.g., |
Square matrix of biological complexes linked by one or more interacting proteins and normalized by the possible number of interactions between each complex.
N. LeMeur
1 2 3 4 5 6 7 8 | data(Atong)
data(ScISIC)
data(SGA)
SLa2 <- gi2Interactome(Atong, ScISIC)
## Search for synthetic lethal interaction
compM <- getInteraction(SLa2, SGA, ScISIC)
## Normalize
normIntComplex<- normInteraction(compM$bwMat, SGA, ScISIC)
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