npci.index.reconsidered: find targets that have little evidence to be differentially...

Description Usage Arguments Details Value Note Author(s) References See Also Examples

View source: R/precomputefCI.R

Description

the function will be depreciated

Usage

1
npci.index.reconsidered(npci.data, expr.by.fold, null.data.start, diff.data.start, gene.indexes, ctr.indexes, trt.indexes, left.fold, right.fold)

Arguments

npci.data

a data frame containing non-zero numeric values (the data frame must contain more than one row and one column)

expr.by.fold

a 1xN matrix of case-control fold changes for every gene of the total N genes

null.data.start

a Nx1 matrix of control-control fold changes

diff.data.start

a Nx1 matrix of case-control fold changes

gene.indexes

the genes used for differential expression analysis.

ctr.indexes

the control sample column indexes

trt.indexes

the case sample column indexes

left.fold

the minimum fold changes for downregulation

right.fold

the minimum fold changes for upregulation

Details

TBD

Value

values

genes wrongly considered as differentially expressed

Note

TBD

Author(s)

Shaojun Tang

References

http://software.steenlab.org/fCI/

See Also

TBD

Examples

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data.file=data.frame(matrix(sample(3:100, 100*4, replace=TRUE), 100,4))
wt.index=c(1,2)
df.index=c(1,3)
npci=new("NPCI")
npci@wt.index=wt.index
npci@df.index=df.index
npci@sample.data.normalized=data.file
npci=initialize(npci)
npci=normalization(npci)
npci=populate(npci)
npci=compute(npci)
npci=summarize(npci)

npci.data=npci@sample.data.normalized
null.data.start=npci@null.data.start
diff.data.start=npci@diff.data.start
choice=2
rank.index.to.be.removed=npci@rank.index.to.be.removed
expr.by.fold=npci@expr.by.fold

ctr.indexes=1:2
trt.indexes=3:4
use.intersect=FALSE
symmetric.fold=TRUE
fold.cutoff.list=npci@fold.cutoff.list
gene.indexes=npci@diff.gene.ids
left.fold=2
right.fold=2

fCI documentation built on Nov. 8, 2020, 6:53 p.m.