dowser-package: dowser: B Cell Receptor Phylogenetics Toolkit

dowser-packageR Documentation

dowser: B Cell Receptor Phylogenetics Toolkit

Description

Provides a set of functions for inferring, visualizing, and analyzing B cell phylogenetic trees. Provides methods to 1) reconstruct unmutated ancestral sequences, 2) build B cell phylogenetic trees using multiple methods, 3) visualize trees with metadata at the tips, 4) reconstruct intermediate sequences, 5) detect biased ancestor-descendant relationships among metadata types Workflow examples available at documentation site (see URL). Citations: Hoehn et al (2022) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1371/journal.pcbi.1009885")}, Hoehn et al (2021) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1101/2021.01.06.425648")}.

Author(s)

Maintainer: Kenneth Hoehn kenneth.b.hoehn@dartmouth.edu

Authors:

Other contributors:

See Also

Useful links:


dowser documentation built on May 29, 2024, 3:06 a.m.