Description Usage Arguments Details Value References Examples
Imputes the NA values of a scMethrix
object.
1 | impute_by_melissa(scm, threshold = 50, assay = "score", new_assay = "impute")
|
scm |
|
threshold |
The value for cutoff in the "score" assay to determine methylated or unmethylated status. Default = 50 |
assay |
string; name of an existing assay. Default = "score" |
new_assay |
string; name for transformed assay. Default = "new_assay" |
Uses the inputted function to transform an assay in the scMethrix
object
An scMethrix
object
Kapourani CA, Sanguinetti G (2019). “Melissa: Bayesian clustering and imputation of single cell methylomes.” Genome Biology, 20, 61. doi: 10.1186/s13059-019-1665-8.
1 | data('scMethrix_data')
|
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