impute_by_melissa: Imputes the NA values of a 'scMethrix' object.
In CompEpigen/scMethrix: Fast and efficient summarization of single cell whole genome bisulfate data
Description
Usage
Arguments
Details
Value
References
Examples
Description
Imputes the NA values of a scMethrix object.
Usage
1
impute_by_melissa(scm, threshold = 50, assay = "score", new_assay = "impute")
Arguments
scm
scMethrix; the single cell methylation experiment
threshold
The value for cutoff in the "score" assay to determine methylated or unmethylated status.
Default = 50
assay
string; name of an existing assay. Default = "score"
new_assay
string; name for transformed assay. Default = "new_assay"
Details
Uses the inputted function to transform an assay in the scMethrix object
Value
An scMethrix object
References
Kapourani CA, Sanguinetti G (2019). “Melissa: Bayesian clustering and imputation of single cell methylomes.” Genome Biology, 20, 61. doi: 10.1186/s13059-019-1665-8.
Examples
1
data('scMethrix_data')
CompEpigen/scMethrix documentation built on Nov. 6, 2021, 3:09 p.m.
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Description Usage Arguments Details Value References Examples
Description
Imputes the NA values of a scMethrix object.
Usage
1 | impute_by_melissa(scm, threshold = 50, assay = "score", new_assay = "impute")
|
Arguments
scm |
|
threshold |
The value for cutoff in the "score" assay to determine methylated or unmethylated status. Default = 50 |
assay |
string; name of an existing assay. Default = "score" |
new_assay |
string; name for transformed assay. Default = "new_assay" |
Details
Uses the inputted function to transform an assay in the scMethrix object
Value
An scMethrix object
References
Kapourani CA, Sanguinetti G (2019). “Melissa: Bayesian clustering and imputation of single cell methylomes.” Genome Biology, 20, 61. doi: 10.1186/s13059-019-1665-8.
Examples
1 | data('scMethrix_data')
|
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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