CalculateAlleleFrequency: Calculating the Minor Allele Frequency.

In CostaLab/sigurd: Single cell Genotyping Using RNA Data

Calculating the Minor Allele Frequency.

Description

We calculate the MAF from a reference reads matrix and an alternative reads matrix. This function is intended to be used with the mitochondrial genome and not with other somatic mutations.

Usage

CalculateAlleleFrequency(reference_reads, alternative_reads, pseudo_count = 0)

Arguments

reference_reads	Reference reads matrix.
alternative_reads	List of matrices for the alternative reads.
pseudo_count	= What is the pseudo count you want to add to the reference_reads matrix. Default = 0

CostaLab/sigurd documentation built on Feb. 10, 2025, 11:08 p.m.