curatedPCaDatasets_friedrich: Friedrich et al. MAE-object

curatedPCaDatasets_friedrichR Documentation

Friedrich et al. MAE-object

Description

MultiAssayExperiment object containing gene expression (gex) and immune cell estimates for Friedrich et al.

Format

An MAE object spanning 255 men with prostate cancer

gex.logq

matrix with 23097 rows and 255 columns, for the log-quantile normalized gene expression data

cibersort

matrix with 22 rows and 255 columns, of cibersort based deconvolution data

xcell

matrix with 39 rows and 255 columns, of xcell based deconvolution data

epic

matrix with 8 rows and 255 columns, of epic based deconvolution data

quantiseq

matrix with 11 rows and 255 columns, of quantiseq based deconvolution data

estimate

data.frame with 4 rows and 255 columns, of cell types based on ESTIMATE method

scores

matrix with 4 rows and 255 columns, of risk scores and AR scores

mcp

matrix with 11 rows and 255 columns, of mcp-counter based deconvolution data

Details

The data comprises of 255 samples, with 164 primary tumors samples, 52 adjacent normal samples, and 39 benign prostate hyperplasia samples. This dataset includes in its totality the 164 samples analysed in Kreutz et al. 2020.

Value

A MultiAssayExperiment corresponding to the study and its available omics.

Source

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134051

References

(PubMed) (PubMed)

Examples

mae_friedrich <- getPCa('friedrich')

Syksy/curatedPCaData documentation built on Oct. 11, 2024, 7:05 a.m.