curatedPCaDatasets_taylor: Taylor et al. MAE-object

curatedPCaDatasets_taylorR Documentation

Taylor et al. MAE-object

Description

MultiAssayExperiment object containing gene expression (gex), copy number alteration (cna), mutations and immune cell estimates from Taylor et al.

Format

An MAE object spanning 218 men with prostate cancer

cna.gistic

matrix with 17832 rows and 194 columns, of gistic values for copy number alteration data

cna.logr

matrix with 18062 rows and 218 columns, of log-ratios for copy number alteration data

gex.rma

matrix with 17410 rows and 179 columns, of gene expression data

mut

RaggedExperiment with 90 rows and 43 columns, of mutation data

cibersort

matrix with 22 rows and 179 columns, of cibersort based deconvolution data

xcell

matrix with 39 rows and 179 columns, of xcell based deconvolution data

epic

matrix with 8 rows and 179 columns, of epic based deconvolution data

quantiseq

matrix with 11 rows and 179 columns, of quantiseq based deconvolution data

estimate

data.frame with 4 rows and 179 columns, of cell types based on ESTIMATE method

scores

matrix with 4 rows and 179 columns, of risk scores and AR scores

mcp

matrix with 11 rows and 179 columns, of mcp-counter based deconvolution data

Details

Note that there is lack of overlap between the omics provided for each sample.

Value

A MultiAssayExperiment corresponding to the study and its available omics.

Source

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE21035

References

(PubMed)

Examples

mae_taylor <- getPCa('taylor')

Syksy/curatedPCaData documentation built on Oct. 11, 2024, 7:05 a.m.