Find <i>P. falciparum</i> genes that are differentially expressed between field parasites from pregnant women and those from children. <br><br>NSR-seq was used to analyze the transcriptome of an unsynchronized in vitro culture of human malaria parasite P. falciparum reference strain 3D7, and two pools of field isolates from malaria-infected pregnant women and children adapted to short-term in vitro culture and matched by the percentage of rings, thophozoites and schizonts. <br><br>A gene signature of Plasmodium falciparum parasites infecting children identified by NSR-seq transcriptional profiling. Marissa Vignali, Christopher D. Armour , Jingyang Chen, Robert Morrison, John C. Castle, Matthew C. Biery, Heather Bouzek, Wonjong Moon, Tomas Babak, Michal Fried, Christopher K. Raymond and Patrick E. Duffy. Submitted
RNA_pfal_fc_two_pd |
the reference sample |
RNA_pfal_fc_one_pd |
the comparison sample |
fold_change |
Enter a non-negative number. NOTE: Fold change is reported in the summary as positive numbers for up-regulated genes and negative numbers for down-regulated genes |
regulated_dir |
For ConditionA vs. ConditionB, select up-regulated for genes where ConditionA > ConditionB and select down-regulated for genes where ConditionB > ConditionA. |
minimum_percentile_value |
Enter a number for the minimum percentile value of the reference if down-regulated or the comparator if up-regulated the selected samples must meet in order to be included in the fold change calculation. |
o-fields |
Single valued attributes of the feature. Provide one or more values. Use comma as a delimter. |
o-tables |
Multi-valued attributes of the feature. Provide one or more values. Use comma as a delimter. |
.convert |
a logical value or a function that controls how the result of the method is returned. If this is a function, the character string or raw vector is passed to this function and it converts it appropriately. If this is a logical value and |
.url |
the URL for the Web request. This defaults to the correct value, but can be specified by the caller if the method is available at a different URL, e.g. locally or in a mirror server. |
.json |
a logical value controlling whether to use the JSON or the XML version of the method |
text/xml text/plain
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