sysGTRDtf: sysGTRDtf.
In hyginn/BCB420.2019.ESA: Exploratory Systems Analysis Tools

Description Usage Arguments Value Details Author(s) See Also Examples

sysGTRDtf Fetch GTRD data for the specified Transcription Factors and genes.

1	sysGTRDtf(TfSym, GeneSym)

`TfSym`	(character) A vector of length > 0L of unique TFs (HGNC symbols) that was extracted from the output of sysGTRDgenes() for a certain set of genes.
`GeneSym`	(character) A vector of length > 0L of the unique genes (HGNC symbols) that the function sysGTRDgenes() retrieved for an input of a certain set of genes (the same certain set of genes that was used to produce TfSym).

(list) A list of transcription-factor-named character vectors of the genes that bind each transcription factor.

This is a helper function. The fetched dataset was collected and composed from the GTRD database. The GTRDTFgenes dataset lists which genes bind each specified TF, as observed by ChIP-seq experiments. For more details about the function that fetches the GTRDTFgenes database, see fetchData. This function requires an input that can be produced by the helper function sysGTRDgenes.

Sapir Labes (aut)

fetchData Fetches the requested dataset.

## Not run: 
# Fetching the vector of the genes that bind the transcription factor AR.
GTRDgenes <- sysGTRDgenes(GeneSym = c("LAMP1", "HDAC6"))
mySymbols <- names(GTRDgenes) #The specific set of genes retrieved
myTfSym <- unique(unlist(GTRDgenes, use.names = FALSE)) #TFs that bind the specific set of genes
sysGTRDtf(TfSym = myTfSym, GeneSym = mySymbols)

## End(Not run)