Description Usage Arguments Value Examples
View source: R/cluster_functions.R
Applies agglomerative hierarchical clustering to a transcriptomics dataset and appends a cluster column to this dataset for all genes.
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dataset |
A transcriptomics dataset. First columns should be gene names. All other columns should be expression levels. Not needed if an argument to distance is given. |
distance |
A distance matrix. If a distance matrix has already been
created (such as by using the |
k |
The total number of clusters. |
metric |
The distance metric to be used to calculate the distances between genes. See parallelDist::parDist for all accepted arguments. |
nthreads |
Number of processor threads to be used for calculating the distance matrix. If not specified then the maximum number of logical cores are used. |
scale |
If the gene activity should be scaled before clustering. |
center |
If the gene activity should be centered before clustering. |
Returns transcriptomics dataset provided with additional cluster column appended denoted which cluster each gene belongs to.
1 | pam.df <- AgglomClustering(Laurasmappings, k = 10, nthreads= 2)
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